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홍수희 교수님

홍수희 교수님
  • 전공 : 해양면역공학
  • 직급 : 교수
  • 연구실 : N17-309호
  • 전화번호 : 033-640-2852
  • 이메일 : s.hong@gwnu.ac.kr
  • 연구분야 : 분자면역학(Cytokine)

학력

1989.3 - 1993.2 : 부경대학교 어병학과 이학사 1994.3 - 1996.2 : 부경대학교 어병학과 이학석사 1998.10 - 2002.6 : Univ. of Aberdeen 동물학과 이학박사

경력

2002.3 - 2003.11 : 국립수산과학원 생명공학연구단 Post Doc. 항질병 유전자 기능 연구 2004.3 - 2006.2 : Kangnung-Wonju National University, Full time Lecturer 2006.3 - 2010.2 : Kangnung-Wonju National University, Assistant Professor 2006.12 - 2008.2 : Kangnung-Wonju National University, Head of Marine Biotechnology Department 2007.3 - 2008.2 : Kangnung-Wonju National University, Director of Marine Bioscience and Technology Division 2010.3 - 2015.2 : Kangnung-Wonju National University, Associate Professor 2015.3 - present : Kangnung-Wonju National University Professor

전문연구분야

분자면역학(Cytokine)

어병학

주요논문 - SCI PUBLICATIONS

1.Yong Yang, Jongwon Lim, Changshen Li, Sangmin Lee, Suhee Hong Effects of sulfated polysaccharides isolated from Codium fragile on inflammatory cytokine gene expression and Edwardsiella tarda infection in rockfish, Sebastes schlegelii. Fish & shellfish immunology, 112, 125-135, 2021 2.Jinwoo Kim, Miyoung Cho, Kwang Il Kim, Eun Young Min, Jongwon Lim, Suhee Hong Transcriptome profiling in head kidney of rainbow trout (Oncorhynchus mykiss) after infection with the low virulent Nagano genotype of infectious hematopoietic necrosis virus. Archives of Virology, 2021 3.Woo Ju Kwon, Jae Chan Choi, Suhee Hong, Young Chul Kim, Min Gyeong Jeong, Joon Gyu Min, Joon Bum Jeong, Kwang Il Kim, Hyun Do Jeong Development of a high-dose vaccine formulation for prevention of megalocytivirus infection in rock bream (Oplegnathus fasciatus), Vaccine, 8107-8115, 2020 4.Woo Ju Kwon, Min Ji Yoon, Ji Woong Jin, Kwang Il Kim, Young Chul Kim, Suhee Hong*, Joon Bum Jeong, Hyun Do Jeong Development and characterization of megalocytivirus persistently-infected cell cultures for high yield of virus. Tissue and Cell, 66, 101387, 2020 5.Jongwon Lim, Taehoo Park, Jinwoo Kim, Suhee Hong Cloning and characterization of tumor necrosis factor superfamily 15 in rock bream, Oplegnathus fasciatus; phylogenetic, in silico, and expressional analysis Developmental & Comparative Immunology, 108, 103685, 2020 6.Jongwon Lim, Suhee Hong Characterization of A. salmonicida and A. sobria isolated from cultured salmonid fish in Korea and development of a vaccine against furunculosis Journal of Fish Diseases, 609-620, 2020 7.Suhee Hong, Ting-Yu Wang, Christopher J. Secombes, Tiehui Wang Different origins of paralogues of salmonid TNFR1 and TNFR2: Characterisation and expression analysis of four TNF receptor genes in rainbow trout Oncorhynchus mykiss. Developmental & Comparative Immunology Volume 99, 2019 8.Y Yang, J Park, SG You, S Hong Immuno-stimulatory effects of sulfated polysaccharides isolated from Codium fragile in olive flounder, Paralichthys olivaceus Fish & shellfish immunology, 2019 9.Jinhwan Park, Wooju Kwon, Wi-Sik Kim, Hyun-Do Jeong, Suhee Hong Cloning and expressional analysis of secretory and membrane-bound IgM in rock bream (Oplegnathus fasciatus) under megalocytivirus infection and vaccination Fish & Shellfish Immunology Volume 87, 275-285, 2019 10.JW Jin, YK Kim, S Hong, YC Kim… Identification and Characterization of Megalocytivirus Type 3 Infection with Low Mortality in Starry Flounder, Platichthys stellatus, in Korea Journal of the World …, 2018 11.SR Hong, MS Kim, HD Jeong, S Hong Development of real‐time and quantitative QCM immunosensor for the rapid diagnosis of Aeromonas hydrophila infection. Aquaculture research, 2017 12.M-S Kim, D-H Hur, S-M Lee, E Jeoung, H D Jeong, Suhee Hong Effect of Vitamin E with Different Levels or Sources of Dietary Lipid on the Growth and the Expression of Inflammatory, Oxidative stress and Apoptotic Genes in Head Kidney of Olive flounder (Paralichthys olivaceus). Journal of world aquaculture society, 2017 13.J W Jin, Y C Kim, Suhee Hong, M S Kim, J B Jeong, H D Jeong Cloning and expression analysis of innate immune genes from red sea bream to assess different susceptibility to megalocytivirus infection. Journal of Fish Diseases, 2017 14.김광일, 권우주, 김영철, 김명석, 홍수희, 정현도Surveillance of aquatic animal viruses in seawater and shellfish in Korea. AQUACULTURE, 2016 15.홍수희, 진지웅, 박재헌, 김중균, 정현도 Analysis of proinflammatory gene expression by RBIV infection in rock bream, Oplegnathus faciatus. Fish & Shellfish Immunology, 2016 16.조미영, 원경미, 김진우, 지보영, 박명애, 홍수희 Detection of koi herpesvirus (KHV) in healthy cyprinid seed stock. Diseases of Aquatic Organisms, 2014 17.T Wang, M Husain, S Hong, J Holland Differential expression, modulation and bioactivity of distinct fish IL-12 isoforms: Implication towards the evolution of Th1-like immune responses. European J Immunology, 44(5), 1541-1551, 2014 18.김명석, 진지웅, 한현자, 최혜승, 홍수희, 조지영Genotype and virulence of Streptococcus ininae isolated from diseased olive flounder. Fisheries Science, 2014 19.S Hong, L Li, Q Xu, C Secombes, T Wang Two Types of TNF-a Exist in Teleost Fish: Phylogeny, Expression, and Bioactivity Analysis of Type-II TNF-a3 in Rainbow Trout Oncorhynchus mykiss (J. Immunology, 2013, 191, 5959-5972) 20.DH Hur, S Hong Cloning and characterization of a fish specific gelsolin family gene, ScinL, in olive flounder (Paralichthys olivaceus).(Comparative Biochemistry and Physiology B, 2013, 164, 89-98) 21.DH Hur, S Hong Analysis of immune gene expression modulated by benzo[a]pyrene in head kidney of olive flounder (Paralichthys olivaceus) (Comparative Biochemistry and Physiology B, 2013, 165, 49-57) 22.SR Hong, HD Jeong, S Hong QCM DNA biosensor for the diagnosis of a fish pathogenic virus VHSV, Talanta, 82(3), 899-903, 2010 23.JK Lee, JK Jeon, SK Kim, S Hong, HK Hyun Purification and characterization of angiotensin I converting enzyme inhibitory peptides from the rotifer, Brachionus rotundiformis Bioresource Technology, 100(21), 5255-5259, 2009 24.S Hong, C. Secombes Two peptides derived from trout IL-1beta have different stimulatory effects on immune gene expression after intraperitoneal administration. Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology 153 (3) 275-280, 2009 25.SR Hong, SJ Choi, HD Jeong, S Hong Development of QCM biosensor to detect a marine derived pathogenic bacteria Edwardsiella tarda using a novel immobilisation method. Biosensors & Bioelectronics, 24(6) 1635-1640, 2009 26.HJ Cho, RJ Jeon, JK, Jeong, JB Jeong, S Hong, HD Jeong, Tansmission of iridovirus from freshwater ornamental fish to marine fish. DISEASES OF AQUATIC ORGANISMS, 82(1), 27-36, 2008 27.Application of Advanced Materials with a Meta stable Phase on Functional Devices and Bio-sensors Solid State Phenomena 124-126, 219-222, 2007 28.Lee D-S, Hong S, Lee H-J, Jun LJ, Chung JK, Kim KH, Jeong HD. Molecular cDNA cloning and analysis of the organization and expression of the IL-1b gene in the Nile tilapia, Oreochromis niloticus. Comparative Biochemistry and Physiology, 2006, 143(3), 307-314 29.Kim Y-O, Hong S, Nam B-H, Lee J-H, Kim K-K, Lee S-J Molecular cloning and expression analysis of two hepcidin genes from olive flounder Paralychthys olivaceus. Biosci. Biotechnol. Biochem., 69(7), 2005, 1411-1414 30.Hong, S., Zou, J., Bols, N.C. & Secombes, C.J. Analysis and characterisation of IL-1β processing in trout, Oncorhynchus mykiss. Fish & Shellfish Immunol., 2004, 16(3), 453-459. 31.JB Jeong, KH Park, KY Kim, S Hong, KH Kim, JK Chung, JL Komisar, HD Jeong Multiplex PCR for the diagnosis of red sea bream iridoviruses isolated in Korea. Aquaculture, 235,2004, 139-152 32.Hong S, Peddie S, Campos-Perez JJ, Zou J, Secombes CJ. The effect of intraperitoneally administered recombinant IL-1b on immune parameters and resistance to Aeromonas salmonicida in the rainbow trout (Oncorhynchus mykiss). Dev. Comp. Immunol. 2003, 27(9), 801-12 33.Hong S, Zou J, Crampe M, Peddie S, Scapigliati G, Bols N, Cunningham C, Secombes CJ. The production and bioactivity of rainbow trout (Oncorhynchus mykiss) recombinant IL-1β. Vet. Immunol. Immunopathol. 2001, 81(1-2), 1-14. 34.Laing KJ, Wang T, Zou J, Holland J, Hong S, Bols N, Hirono I, Aoki T, Secombes CJ. Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor-alpha. Eur. J. Biochem. 2001, 268(5), 1315-1322. 35.Secombes CJ, Wang T, Hong S, Peddie S, Crampe M, Laing KJ, Cunningham C, Zou J. Cytokines and innate immunity of fish. Dev. Comp. Immunol. 2001, 25(8-9), 713-23. 36.J. Zou, T. Wang, S. Hong, C. Cunningham and C. J. Secombes Role of interleukin-1 in immune responses of rainbow trout, Fish & Shellfish Immunology, 2000, 10(3), 289 37.Secombes, C.J., Bird, S., Hong, S., Laing, K.J. & Zou, J. (2001). Phylogeny of vertebrate cytokines. In "Phylogenetic perspectives on the vertebrate immune system" (Ed by G. Beck, M. Sugumaran & E.L. Cooper), Copper Mountain, July 1999. Adv. Exp. Med. Biol. 484: pp. 89-94. Kluwer Academic/Plenum Publishers, New York.

주요논문 - NON-SCI PUBLICATIONS

1.임종원, 구본근, 한현자, 김위식, 홍수희 강원도 양식 연어과 어류에서 분리된 에로모나스 종의 유전학적 동정, 한국어병학회지, 2017 2.양용, 홍수희 Immuno-stimulatory Effects of Sulfated Polysaccharides Isolated from Codium fragile on Interleukin-1β Gene Expression in Olive Flounder, Paralichythys olivaceus 해양생명과학회지, 2017 3.김명석, 정승희, 홍수희, 정현도 characteristics an pathogenicity for japanese eel of Vibrio vulnificus isolated from oyster, sediment and seawater in the Korea coast. Fisheries and Aquatic Sciences, 2015 4.김명석, 진지웅, 정승희, 서정수, 홍수희 Genetic variations of outer membrane protein genes of Vibrio harveyi isolated in Korea and immunogenicity of OMPW in olive flounder 수산해양교육연구 2015 5.김명석, 정승희, 홍수희 Vibrio harveyi 백신의 효능 향상을 위한 배양 배지내2-2'-dipyridyl 첨가 및 연쇄구균 백신과 혼합 투여의 효과 수산해양교육연구, 2014 6.홍수희, 정현도 Development of piezoelectric immunosensor for the rapid detection of marine derived pathogenic bacteria, Vibrio vulnificus. Journal of fish pathology, 2014 7.허덕회, 이상민, 홍수희 Effects of dietary lipid sources on apoptotic and immune gene expression in head kidney of olive flounder (Paralichthys olivaceus) 한국어병학회, 2012, 25(3), 199-210 8.진지웅, 남정희, 김광일, 홍수희, 변주영, 정현도 Characterization of the Repetitive Sequences Present in the ORF25 Genomic Region of Megalocytiviruses from Ornamental Fishes 한국수산과학회, 2011, 44(4), 352-358 9.김경덕, 서주영, 홍수희, 김정호, 변희국, 김강웅, 손맹현, 이상민Effects of Dietary Inclusion of Various Additives on Growth Performance, Hematological Parameters, Fatty Acid Composition, Gene Expression and Histopathological Changes in Juvenile Olive Flounder Paralichthys olivaceus 한국수산학회, 2011, 44(2), 141-148 10.S. Hong Production and bioactivity of recombinant tilapia IL-1β J.Fish Pathol. 2009, 22(2), 147-153 11.Hong, S., Lee, S.J., Ahn, K.J, Kim YO Survey of the expression pattern and immunostimulatory effect of DNA vaccine using -galactosidase reporter system in olive flounder. Fisheries science and technology, 7(2), 2004, 70-75 12.Hong, S., Lee, S.J. Survey of the heterogeneous gene expression in olive flounder muscle using the luciferase reporter gene system. J.Fish Pathol. 2003, 147-152 13.Hong S, Lee JH, Kim HW, Kim YO, Kim KK GFP gene expression in transfected rainbow trout fibroblast cell line RTG-2 using a polycationic reagent (Superfect). J.Fish Pathol., 2003, 16(2), 69-73 14.Kim JW, Jee JH, Hong S, Kang JC Hematological changes of olive flounder, Paralichthys Olivaceus exposed to Aroclor 1254. Korean J. Environ. Biol., 2003, 21(2), 114-119 15.김명석, 정승희, 홍수희 Vibrio harveyi 백신의 효능 향상을 위한 배양 배지내2-2'-dipyridyl 첨가 및 연쇄구균 백신과 혼합 투여의 효과 한국수산해양교육학회 16.홍수희, 정현도Development of piezoelectric immunosensor for the rapid detection of marine derived pathogenic bacteria, Vibrio vulnificus 한국어병학회 2014 17.홍수희 Immune gene expression following LPS exposure in the gill of rainbow trout, Oncorhynchus mykiss 한국어병학회 2005, 18(3), 287-292 18.홍수희 정현도 Biological effect of recombinant IL-1β on the expression of antiviral genes in the gill of rainbow trout, Oncorhynchus mykiss 한국어병학회지 16(3), 139-146 19.홍수희 정현도 Proinflammatory Effects of Bacterial Lipopolysaccharide (LPS) in Rainbow Trout (Oncorhynchus mykiss) Macrophage Cells 한국수산학회 2003 6(3) 130-134 20.Hematological changes of olive flounder, Paralichthys Olivaceus exposed to aroclor 1254 2003, 21(2) 114-119 21.홍수희 어류질병 방역 대책과 면역 증강 한국양식학회, 2003, 15(1), 51-58

저서

Secombes, C.J., Bird, S., Hong, S., Laing, K.J. & Zou, J. (2001). Phylogeny of vertebrate cytokines. In "Phylogenetic perspectives on the vertebrate immune system" (Ed by G. Beck, M. Sugumaran & E.L. Cooper), Copper Mountain, July 1999. Adv. Exp. Med. Biol. 484: pp. 89-94. Kluwer Academic/Plenum Publishers, New York.

학회활동

Member of International Society of Developmental and Comparative Immunology Member of World Aquaculture Society Member of Korean Fish Pathology society Member of International Society of Developmental and Comparative Immunology Member of International Society of Fish and Shellfish Immunology Member of World Aquaculture Society

특허

1.최병학, 최석정 ,홍수희, 이성철 다중 신호처리가 가능한 미세 질량 측정 시스템(Microbalance system for Multiple signal processing) 2011, 0-1016140-0000 2.피조 단결정 신소재 진동자를 적용한 고감도 나노밸러스의 제조방법 2007 출원번호 2007-117562 3.나노 다공성 전극을 이용한 고감도 마이크로밸런스 및 그 제조 방법 10-2007-0025606 4.홍수희, 이상민, 임종원 고병원성 에어로모나스 살모니시다 RTDH(Aeromonas salmonicida RTDH) 균주 및 이를 이용한 백신 조성물. 2021, 등록번호 10-2199932-0000

해양생물면역공학연구실

지도교수 : 홍수희 교수 위치 : 생명과학대학 2호관 309호 연락처 : 033-640-2842

연구 분야 소개

- 분자생물학적 어류면역반응분석 - 면역생리활성물질 탐색 및 활성측정 - 어류유전자 클로닝 및 발현 분석 - 재조합단백질 생산 및 생리활성측정 - 진단 및 환경감시용 분자마커의 개발 - 진단용 바이오센서시스템의 개발

주요 활동

  • 환경호르몬 등 각종 오염물질이 해양생물에게 미치는 영향

    어류의 유전자 클로닝 및 발현 분석

  • 해양생물이 가지고 있는 자연독에 관한 연구

    항체 제작

  • 해양생물이 가지고 있는 자연독에 관한 연구

    바이오센서 실험